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在初步阐明了5-HT导致中枢疲劳的机制之后,目前的中枢性运动疲劳的研究趋势主要是明确5-HT及5-HT受体在不同脑区的作用,5-HT受体拮抗剂与促进剂的作用。在此基础上更开展了很多通过营养或运动干预手段延缓与消除中枢疲劳的研究。随着神经生理学研究方法的改进,目前已经可以使用脑内微透析技术等方法进行活体动物神经递质的采样,达到动态检测运动中脑内神经递质变化的目的。国内使用新技术新方法研究中枢性运动疲劳还有待于进一步发展。
After the initial elucidation of the mechanism of 5-HT leading to central fatigue, the current research trend of central fatigue is to clarify the role of 5-HT and 5-HT receptors in different brain regions. The effects of 5-HT receptor antagonists Promoter role. On this basis, many studies have been carried out to delay and eliminate central fatigue through nutritional or exercise interventions. With the improvement of neurophysiological research methods, it is now possible to sample neurotransmitters of live animals using methods such as intracerebral microdialysis to achieve the purpose of dynamically detecting changes of neurotransmitters in the brain during exercise. The domestic use of new technologies and new methods of studying central sports fatigue needs to be further developed.