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本文研究的目的是要了解抑郁症与颞下颌关节疼痛—功能紊乱综合征患者治疗效果间的关系。材料和方法本研究共有64例患者,均诊断为颞下颌关节疼痛—功能紊乱综合征。依据临床表现和Ham-ilton Rating分级,将患者分为无抑郁症组(组_1)和抑郁症组。无抑郁症组仅接受(牙合)夹板治疗。抑郁症组又分为三组:单用(牙合)夹板治疗组(组_2)单用抗抑郁药物治疗组(组_3),(牙合)夹板与药物同时治疗组(组_4)。结果与讨论各组在治疗开始及第四周时平均疼痛分级无显著性差异。在第八周时各组在平均分级上有显著性差异(P<0.05)。组_1和组_4的疼痛症状继续明显改善,组_2与组_3则停留在某一水平上。方差分析,抑郁症组(组_2,组_3,组_4)之间有显著差异。组_4疗效最好,组_3次之,组_2最差。抑郁症组中同时使用(牙合)夹板和药物治疗的(组_4)与无抑郁症(组_1)之间无显著性差异,疼痛症状都能迅速改善。
The purpose of this study is to understand the relationship between depression and the therapeutic effect of temporomandibular joint pain-dysfunction syndrome. Materials and Methods A total of 64 patients in this study were diagnosed as temporomandibular joint pain-dysfunction syndrome. Patients were classified into the group without depression (group_1) and the group with depression according to clinical manifestations and Ham-ilton Rating. No depression group only received (occlusion) splint treatment. The depression group was further divided into three groups: single anti-depressant drug group (group 3), occlusal splint group and drug simultaneous treatment group (group 4) ). Results and Discussion There was no significant difference in average pain grade between the beginning of treatment and the fourth week in each group. There was a significant difference in the mean grading between the groups on the eighth week (P <0.05). Group 1 and group 4 pain symptoms continued to improve significantly, group _2 and group _3 stay at a certain level. Analysis of variance, depression group (group _2, group _3, group _4) were significantly different. Group _4 the best effect, group _3 times, group _2 worst. There was no significant difference between depression group (group_4) and non-depression group (group_1) using both occlusal splint and drug therapy, and the pain symptom could be rapidly improved.