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菜粉蝶颗粒体病毒(PrGV)与多种低浓度的化学杀虫剂混用,对莱青虫的毒力具有明显的增效作用。PrGV与乙酰甲胺磷混用对菜青虫的防治效果和作物的保护率均优于单用PrGV或乙酰甲胺磷,并且混剂中化学杀虫剂的用量也可减少30％～50％。初步认为PrGV感染对虫体乙酰胆碱酯酶(AChE)。多功能氧化酶(MFO)活性的降低是混剂增效的内在原因之一。经PrGV感染的5龄虫,AChE活性降低了37.94％,MFO活性也下降了55.37～78.78％。病毒感染也影响到杀虫剂对MFO活性的诱导作用。由于MFO活性较低,其对药剂的降解力也随之下降,因此有更多杀虫剂可到达作用靶标AChE,进一步抑制原来活性已较低的感染病毒虫体的AChE的活性。
Cabbage butterfly granular virus (PrGV) mixed with a variety of low concentrations of chemical insecticides on the virulence of larvae have obvious synergies. The combination of PrGV with acephate has better control effect on cabbage pests and the protection rate of crops than PrGV alone or acephate, and the dosage of chemical insecticide in mixture can be reduced by 30% ~ 50%. PrGV was initially thought to be infected with the parasite acetylcholinesterase (AChE). Reduction of multifunctional oxidase (MFO) activity is one of the intrinsic causes of the synergistic effect of the mixture. After 5-instar larvae infected with PrGV, the AChE activity decreased by 37.94% and the MFO activity decreased by 55.37-78.78%. Viral infections also affect the induction of MFO activity by pesticides. Due to the low activity of MFO, its degradability to the drug also decreases. Therefore, more insecticides can reach the target AChE and further inhibit the AChE activity of the original virus-infected worms.