论文部分内容阅读
研究肝癌动物模型的ＣＯ２超声造影（ＣＯ２－ＥＵＳ），以探讨经肝动脉和经门脉ＣＯ２－ＥＵＳ在诊断肝癌中的差异及可行性。３６只接种Ｗａｌｋｅｒ－２５６瘤株的肝癌鼠分两组，分别行肝动脉和门脉途径的ＣＯ２－ＥＵＳ。结果：鼠肝癌在经肝动脉ＣＯ２－ＥＵＳ中可表现高回声、低回声、斑块及环状增强４种类型，可根据不同表现提示肿瘤坏死与否等情况。经门脉 ＣＯ２－ＥＵＳ均显示肝癌为低回声型，并不能提示肿瘤内病理改变等情况。结论：两种方法的ＣＯ２－ＥＵＳ均可提高小肝癌的检出（最小为３ｍｍ），而经肝动脉ＣＯ２－ＥＵＳ可反映肿瘤内血供情况。
To study the CO2 contrast-enhanced ultrasound (CO2-EUS) in liver cancer animal models to investigate the difference and feasibility of trans-hepatic artery and portal vein CO2-EUS in the diagnosis of liver cancer. Thirty-six hepatocarcinomas that inoculated with Walker-256 tumors were divided into two groups and were treated with CO2-EUS of the hepatic artery and portal vein respectively. RESULTS: Rat hepatocellular carcinoma showed high echo, hypoechoic, plaque and annular enhancement in the hepatic artery CO2-EUS, suggesting tumor necrosis or not according to different performances. The portal vein CO2-EUS showed that the liver cancer was hypoechoic and did not suggest pathological changes in the tumor. Conclusions: CO2-EUS of both methods can increase the detection of small hepatocellular carcinoma (minimum 3 mm), and transhepatic artery CO2-EUS can reflect the blood supply within the tumor.