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本实驗选用兔子和鴿子,每天飼喂胆固醇,以建立动脉粥样硬化的模型。兔比鴿更易形成病变,但較易死亡。兔每天飼喂胆固醇3克/公斤历3个月的模型似乎較有把握:但每天飼喂0.5克/公斤历4个月的模型,应重复实驗証实。兔加飼硫氧嘧啶、苯丙胺、烟碱、維生素D2、乳酸鈣、胆酸鈉和蔗糖,可促进病变的形成,惟剂量不宜过大。鴿子模型以每天喂胆固醇3克/公斤加甲基硫氧嘧啶0.1克的斑块为較多。从喂胆固醇第2月开始每天飼喂4种治疗药物,結果以二仙合剂和肉桂酸鈉似較苯乙肼和三顆針更有希望。
This experiment selected rabbits and pigeons, fed cholesterol every day to establish atherosclerosis model. Rabbits are more likely to develop lesions than pigeons, but are more likely to die. Rabbits fed cholesterol 3 g / kg for 3 months seemed more confident with their daily feeding: a model fed 0.5 g / kg for 4 months per day should be replicated experimentally. Rabbits fed with thiamine, amphetamine, nicotine, vitamin D2, calcium lactate, sodium cholate and sucrose, can promote the formation of lesions, but the dose should not be too large. The pigeon model is fed with 3 g / kg of cholesterol and 0.1 g of methylthiouracil daily for more. Feeding cholesterol from the beginning of February every day feeding four kinds of treatment drugs, the results with Erxian mixture and sodium cinnamate than phenelzine and three needles more hope.