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自六十年代无胸腺裸小鼠(以下简称裸鼠)问世以来,裸鼠作为医学科研特别是肿瘤学和免疫学领域中的动物模型得到日益广泛的应用。由于裸鼠缺乏正常胸腺,T细胞缺损,免疫性能低,导致对微生物环境的高度敏感及饲养繁殖的困难。在普通动物房条件下,裸鼠平均生存期只有14～30天,但在无病条件下其生存期能增加一年以上,根据美国专家制定的“医学生物学研究中无胸腺裸鼠管理及应用指南”所提要求,如何设计隔离屏障,并能较长时间的维持无病条件,至关重要。为满足本校科研工作需要,提供较大数量的合格裸鼠,我校实验动物科
Since the advent of athymic nude mice (hereinafter referred to as nude mice) in the 1960s, nude mice have been widely used as animal models in medical research, especially in the field of oncology and immunology. Due to the lack of normal thymus nude mice, T cell defects, low immunity, resulting in a highly sensitive to the microbial environment and feeding and breeding difficulties. In general animal room conditions, the average survival of nude mice only 14 to 30 days, but in disease-free conditions, its survival can increase more than one year, according to the United States developed a medical experts in the study of athymic nude mice management and Application Guide "to the requirements, how to design the isolation barrier, and can maintain a disease-free condition for a long time, it is very important. To meet the needs of our scientific research work, to provide a larger number of qualified nude mice, our laboratory Animal Section