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随着血液透析技术的应用和进步,慢性肾功能衰竭(CRF)患者的预期寿命也在逐步提高,患者不再单纯满足于寿命的延长,也逐渐要求提高生活质量。勃起功能障碍(ED)作为一个影响生活质量的重要因素,也是CRF患者面临的重要问题之一。引起CRF患者ED的病理生理机制繁多,主要包括周围血管性病变、神经调节异常及内分泌代谢紊乱。本文针对CRF患者ED的病理生理机制研究进行综述,以期进一步提高CRF患者ED的研究水平和治疗效果。
With the application and progress of hemodialysis, the life expectancy of patients with chronic renal failure (CRF) is gradually increasing. Patients are no longer simply satisfied with the extension of their life expectancy, but also gradually seek to improve their quality of life. Erectile dysfunction (ED), as an important factor affecting the quality of life, is also one of the important problems faced by CRF patients. The pathogenesis of ED in patients with CRF has many pathophysiological mechanisms, including peripheral vascular lesions, abnormal neuromodulation and endocrine and metabolic disorders. This article reviews the pathophysiological mechanisms of ED in patients with CRF, in order to further improve the level of ED research and treatment of CRF patients.