Evaluation of Antibody-Dependent Enhancement of SARS-CoV Infection in Rhesus Macaques Immunized with

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Dear Editor,rnIn 2003,severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in Guangdong Province,China,infected more than 8000 individuals,and resulted in a 10% mortality rate (Rota et al.2003).Later,in 2012,a novel CoV,Middle East respiratory syndrome coronavirus (MERS-CoV),was isolated from the sputum of a man in Saudi Arabia (Perl et al.2014).Notably,MERS-CoV recently reemerged in the Republic of Korea,and killed 36 out of 186 confirmed cases (Korea Centers for Disease Control and Prevention 2015).Therefore,SARS-CoV still carries the potential for resurgence;efforts are being made to prevent the recurrence of an epidemic.
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