无论口服或注射用药,药物皆作用于患者整个机体。在对恶性肿瘤进行治疗时,人们只希望药物作用于靶部位(或靶细胞),而对正常细胞无损。但目前使用的抗肿瘤药物却无选择性,它们除能杀灭部分癌细胞外,同时亦杀伤和抑制正常细胞,常使患者机体蒙受很大损伤,甚至难以继续治疗。为克服这一障碍,多年来不少学者对药物如何导向靶部位,进行了大量探索。近10多年来,此项工作已有一些进展,现概述如下。一、磁性微粒应用磁学原理,将铁磁性颗粒包于含药微球或微囊内,用药后借助于体外磁场效应,使 Whether oral or injectable, the drugs act on the entire body of the patient. In the treatment of malignant tumors, one only hopes that the drug will act on the target site (or target cell), but not on normal cells. However, the currently used anti-tumor drugs are not selective. In addition to killing some cancer cells, they also kill and inhibit normal cells, often causing the patient’s body to suffer great damage, and it is even difficult to continue treatment. In order to overcome this obstacle, many scholars have conducted many explorations over how drugs lead to target sites over the years. In the past 10 years, some progress has been made in this work. The summary is as follows. First, the use of magnetic particles of magnetic principles, the ferromagnetic particles wrapped in drug-containing microspheres or microcapsules, medication after the use of magnetic field effects, so that