浸润性乳腺癌一旦可触知,即是潜在的致命性疾病。恶性细胞很可能由血管和淋巴途径种植,在全身各部位及区域淋巴结形成“微转移”。一旦肿瘤已全身扩散,局部治疗,不管怎样的根治性手术,疗效都不好。作者认为浸润性乳腺癌使用三苯氧胺全身治疗可获得长期治愈。早在1966年已发现其有对抗雌激素的作用。三苯氧胺用在老年乳腺癌妇女的价值现已确定。对照随机试验发现其作用类似于己烯雌酚的药理剂量,但无己烯雌酚的副作用。由于这个原因,三苯 Once invasive breast cancer is palpable, it is a potentially fatal disease. Malignant cells are most likely to be grown by vascular and lymphatic pathways, which form “micrometastases” in various parts of the body and in regional lymph nodes. Once the tumor has spread throughout the body, local treatment, no matter what kind of radical surgery, the efficacy is not good. The authors believe that tamoxifen systemic treatment of invasive breast cancer can be long-term cure. As early as 1966 it was found to have an anti-estrogen effect. The value of tamoxifen in elderly women with breast cancer has now been determined. A controlled randomized trial found that its effect was similar to the pharmacological dose of diethylstilbestrol but no side effects of diethylstilbestrol. For this reason, triphenyl