本文报道3例阑尾原发性腺癌,分别因急性阑尾炎、阑尾周围脓肿及右下腹部肿块而手术,病理检查均证实为阑尾原发性腺癌。镜检显示3例均为结肠型腺癌。其中1例为高分化腺癌,浸润阑尾壁全层,但癌细胞无明显异型性。本文对阑尾原发性腺癌的诊断标准、鉴别诊断及其发生机制进行了讨论。 This article reported three cases of primary adenocarcinoma of the appendix, respectively, due to acute appendicitis, abscess around the appendix and right lower abdomen tumor surgery, pathological examination were confirmed as primary appendix adenocarcinoma. Microscopic examination revealed that all 3 cases had colonic adenocarcinoma. One of them was a well-differentiated adenocarcinoma, infiltrating the entire wall of the appendix, but the cancer cells had no obvious atypicality. This article discusses the diagnostic criteria, differential diagnosis and the mechanism of primary adenocarcinoma of the appendix.