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胰腺肿瘤根据是否出现激素亢进症状及病态分为症状性和无症状性二种。除胰岛素瘤以外的症状性肿瘤,临床上即使确定诊断,多数也有转移和情况不明,不能手术根治,大部分因严重激素亢进症而死亡。1970年以来,由于激素免疫学测定法的普及,影像检查及经皮经肝门静脉采血定位诊断、药物治疗的进步,无转移的早期病例在增加。这杼病例全身状态易改善,故可安全地进行外科切除,治疗效果逐渐提高。不能切除者,可以用药物进行长期控制。尤其胃分泌素瘤的治疗方法有很大改善。本文仅就症状性肿瘤治疗的最新进展,主要以胰岛素瘤和胃分泌素瘤为
Pancreatic tumors are classified as symptomatic and asymptomatic depending on whether or not there is hyperthyroidism. In addition to symptomatic tumors of insulinoma, even if the diagnosis is confirmed clinically, most of them have metastases and the condition is unknown. They cannot be cured by surgery, and most of them die due to severe hyperalgesia. Since 1970, due to the popularization of hormonal immunological assays, imaging examinations, and the advancement of percutaneous transhepatic portal vein location diagnosis and drug therapy, early cases without metastases have increased. In this case, the condition of the entire body is easy to be improved, so surgical resection can be performed safely and the therapeutic effect is gradually improved. Those who cannot be removed can use drugs for long-term control. In particular, the treatment of gastric secretory tumors has been greatly improved. This article is only about the latest developments in the treatment of symptomatic tumors, mainly insulinoma and gastric secretin tumors.