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[目的]探讨中西医结合治疗中心性浆液性脉络膜视网膜病变的效果。[方法]将64例中心性浆液性脉络膜视网膜病变患者随机分为中西医结合组(n=33)和西医组(n=31),两组使用相同西药,中西医结合组同时加用滋养肝肾、健脾化湿、活血祛瘀中药方剂,并在治疗前后分别测定两组血浆儿茶酚胺(CA)含量和组织纤溶酶原激活剂(tPA)、纤溶酶原激活剂抑制物(PAI) 活性。[结果]中西医结合组治愈率为57.58%,西医组治愈率为32.26%(P<0.05)。与治疗前相比,中西医结合组CA含量显著下降(P<0.05),PAI活性亦显著下降(P<0.01),tPA活性显著增高(P<0.01)。与西医组比较,CA、PAI显著降低,tPA活性显著增高(P<0.05~0.01)。[结论]在常规西药治疗的基础上结合滋养肝肾,健脾化湿,活血祛瘀中药较单纯西医治疗更有效。
[Objective] To explore the effect of integrated traditional Chinese and western medicine on central serous chorioretinopathy. [Methods] Sixty-four patients with central serous chorioretinopathy were randomly divided into two groups: integrative medicine group (n = 33) and western medicine group (n = 31). The two groups used the same western medicine. Kidney, spleen and dampness, promoting blood circulation and removing stasis were taken. The levels of plasma catecholamine (CA), tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI) were measured before and after treatment. active. [Result] The cure rate of Integrative Medicine group was 57.58%, and that of Western Medicine Group was 32.26% (P <0.05). Compared with those before treatment, the content of CA in the combination of TCM and WM decreased significantly (P <0.05), the activity of PAI decreased significantly (P <0.01) and the activity of tPA increased significantly (P <0.01). Compared with Western medicine group, CA and PAI were significantly decreased and tPA activity was significantly increased (P <0.05 ~ 0.01). [Conclusion] The combination of nourishing liver and kidney, invigorating the spleen and dampness, promoting blood circulation and removing blood stasis is more effective than western medicine alone on the basis of conventional western medicine.