实验着重观察了川芎嗪与扩血管药物或强心剂配伍应用对慢性缺氧大鼠血气、血流动力学的影响和对肺循环作用的选择性．结果显示：川芎嗪与与强心剂参麦注射液和多巴酚丁胺合用，在降肺动脉压和肺循环阻力方面与川芎嗪单用或川芎嗪与扩血管药物心痛定、ＤＤＰＨ合用效果相似，但对心脏及体循环的副作用则较小；特别是川芎嗪与参麦注射液合用对肺循环的作用有较好选择性．表明川芎嗪与参麦注射液的合用在治疗肺动脉高压方面有一定应用价值． Experiments focused on the tetramethylpyrazine and vasodilator drugs or cardiotonic compatibility application on blood gas and hemodynamics in chronic hypoxic rats and the role of pulmonary circulation selective. The results showed that tetramethylpyrazine was effective in combination with tacrolimus and dobutamine in lowering pulmonary arterial pressure and resistance to pulmonary circulation in combination with tetramethylpyrazine alone or with vasodipine and vasodilator vasodilator, Heart and systemic side effects are smaller; in particular, tetramethylpyrazine and Shenmai injection combination of the role of pulmonary circulation has a better selectivity. Show that the use of tetramethylpyrazine and Shenmai injection in the treatment of pulmonary hypertension have a certain value.