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目的探讨儿科血液病房医院感染的发生原因、临床特点,为降低医院感染的发生提供依据。方法回顾性调查2005年1月-2010年12月医院儿科血液病房住院患儿资料,对医院感染率、感染部位、病原菌及易感因素等进行分析。结果儿科血液病房住院患者3668例,发生医院感染312例,医院感染率为8.51%;感染部位以呼吸道感染为主占45.45%,共查出357株病原菌,易感因素为使用广谱抗菌药物、住院时间≥15d、年龄<1岁、应用糖皮质激素及化疗药物、重症患儿等。结论应针对易感因素,强化医护人员预防医院感染的意识,采取有效的预防控制措施可降低儿科血液病房医院感染发生率。
Objective To investigate the causes and clinical features of nosocomial blood ward hospital infection and provide the basis for reducing the occurrence of nosocomial infection. Methods The data of hospitalized pediatric blood wards from January 2005 to December 2010 were retrospectively analyzed. The infection rate, infection site, pathogens and susceptibility factors were analyzed. Results There were 3668 hospitalized patients in pediatric blood wards, 312 cases of nosocomial infection and 8.51% of hospital infections. The main infection area was respiratory tract infection accounted for 45.45%. A total of 357 strains of pathogens were detected. The predisposing factors were broad-spectrum antibiotics, Hospitalization ≥ 15d, age <1 year, the application of glucocorticoid and chemotherapy drugs, severe children and so on. Conclusion In order to reduce the incidence of nosocomial infection in pediatric blood wards, effective prevention and control measures should be taken in view of the predisposing factors and the awareness of medical staff in preventing nosocomial infections.