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随着非酒精性脂肪肝 (nonalcoholicfattyliver,NAFL)患病率的上升 ,他有可能成为隐原性肝硬化的最主要病因。瘦素 (leptin)是肥胖基因编码的 ,主要由脂肪细胞分泌的一种分泌型激素 ,与NAFL有着密切关系。瘦素或其受体缺陷在动物中可引起严重的肥胖、胰岛素抵抗 (insulinresista
With the rising prevalence of nonalcoholic fatty liver (NAFL), he is likely to be the leading cause of cryptogenic cirrhosis. Leptin, a secreted hormone secreted by fat cells and encoded by obese genes, is closely related to NAFL. Leptin or its receptor defects in animals can cause severe obesity, insulin resistance (insulinresista