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众所周知,白细胞介素-2(IL-2)在机体抗肿瘤免疫中起着重要作用.除IL-2细胞表面受体外,一种被释放到血中的可溶性白细胞介素-2受体(SIL-2R)也与IL-2活性有关.本研究试图评价术后非小细胞肺癌患者血中高水平的SIL-2R与复发率之间的关系.临床资料和方法:60例非小细胞肺癌患者,男56例,女4例,年龄47～72岁(平均61岁).33例鳞癌,27例腺癌.21例有淋巴结受侵(N_12例,N_219例),39例无淋巴结受侵.在研究过程中未接受其它治疗.患者分别于手术前1天、术后7天、术后30天抽血检测SIL-2R
It is well known that interleukin-2 (IL-2) plays an important role in anti-tumor immunity in the body. In addition to IL-2 cell surface receptors, a soluble interleukin-2 receptor is released into the blood ( SIL-2R) is also associated with IL-2 activity. This study sought to evaluate the relationship between high serum levels of SIL-2R and the recurrence rate in patients with non-small cell lung cancer after surgery. Clinical data and methods: 60 patients with non-small cell lung cancer , 56 males and 4 females, aged 47-72 years (average 61 years). 33 cases of squamous cell carcinoma, 27 cases of adenocarcinoma. 21 cases of lymph node invasion (N 12 cases, N 219 cases), 39 cases of no lymph node invasion No other treatment was performed during the study. Patients were tested for SIL-2R 1 day before surgery, 7 days after surgery, and 30 days after surgery.