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返流性食管炎和癌存在着因果关系,作者通过回顾性研究分析两者之间的联系,从中早期发现返流性食管炎的恶变,可以获得早期手术和提高存活时间。材料与方法:在1970年至1988年期间Lille大学Calmette医院对758例症状性胃食管返流患者经药物治疗失败后行手术治疗,其中严重鳞状上皮食管炎136例、Ⅲ级食管炎79例(10.4%)和食管狭窄57例(5.7%)。5例食管炎伴鳞状细胞癌,计男4例,女1例,平均67.2岁(65～70岁)。有食管返流病史平均9.2年(1～30年)。切除标本分类均为T_1N_0M_0。13例食管炎伴腺癌,计男11例,女2例,平均54.5
There is a causal relationship between reflux esophagitis and cancer. The authors conducted a retrospective study to analyze the relationship between the two, and discovered the malignant transformation of reflux esophagitis in the middle and early stages, so as to obtain early surgery and improve survival time. Materials and Methods: During the period from 1970 to 1988, 758 patients with symptomatic gastroesophageal reflux who had failed medical treatment at the Calmette Hospital of Lille University underwent surgical treatment. 136 cases of severe squamous epithelial esophagitis and 79 cases of grade III esophagitis. (10.4%) and esophageal stenosis in 57 cases (5.7%). Five patients with esophagitis and squamous cell carcinoma included 4 males and 1 female, with an average age of 67.2 years (65-70 years). The history of esophageal reflux was 9.2 years (1 to 30 years). The resection specimens were classified as T_1N_0M_0. 13 patients with esophagitis and adenocarcinoma were counted in 11 males and 2 females with an average of 54.5.