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目的:观察参芪扶正注射液联合顺铂治疗肺癌恶性胸腔积液的临床效果。方法:选取经临床病理确诊的肺癌恶性胸腔积液患者60例,随机分为对照组和治疗组。对照组单用顺铂治疗,治疗组在对照组的基础上联合参芪扶正注射液静滴,比较两组的临床疗效、生活质量改善情况(KPS评分)以及不良反应发生情况,对所有临床观察结果进行统计学处理。结果:治疗组有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后的Karnofsky得分明显高于对照组(P<0.05);毒副反应治疗组轻于对照组(P<0.05)。结论:参芪扶正注射液联合顺铂治疗肺癌恶性胸腔积液可明显提高疗效,改善患者的生活质量,减轻化疗毒副反应,值得临床推广应用。
Objective: To observe the clinical effect of Shenqi Fuzheng injection combined with cisplatin in the treatment of malignant pleural effusion of lung cancer. Methods: Sixty patients with malignant pleural effusion of lung cancer diagnosed by clinical pathology were randomly divided into control group and treatment group. The control group was treated with cisplatin alone. On the basis of the control group, the treatment group was treated with intravenous injection of Shenqi Fuzheng, and the clinical efficacy, quality of life (KPS) score and incidence of adverse reactions were compared between the two groups. All clinical observations Results were statistically analyzed. Results: The effective rate of the treatment group was significantly higher than that of the control group (P <0.05); the Karnofsky score of the treatment group was significantly higher than that of the control group (P <0.05) <0.05). Conclusion: Shenqi Fuzheng injection combined with cisplatin in the treatment of malignant pleural effusion of lung cancer can significantly improve the curative effect, improve the quality of life of patients and reduce the toxic and side effects of chemotherapy, which is worthy of clinical application.