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患者,男32岁,船工,1977年12月10日开始口服男性节育药普通棉酚,每日20mg,因服药方法未理解,连服此剂量248天,至8月15日发生软瘫才停药。当时服棉酚总剂量4.96g。患者于7月份开始有乏力、四肢麻木等,发病当天凌晨一点醒来发现双下肢不能动,无力翻身,即抬来我院急诊。体检发现四肢肌张力明显减低,下肢肌力1～2级,上肢肌力2～3级。感觉无明显障碍,腹壁、膝反射消失,跟腱反射减弱,提睾反射存在,病理反射(一);血清钾1.9mEg/L;心电图各联u波明显,V_1-V_4Tu融合u=T,IV_4 T波低平,符合低血钾症。患者服药前体检,心电图均正常,血清钾4.6mEg/L。既往无类似发作史及家族史,当即确诊为低血钾性麻痹,给予补钾治疗,3天后病人四肢活动逐渐恢复,可以下地行走,
Patients, male, 32 years old, boatman, December 10, 1977 Oral male gentian oral gossypol, daily 20mg, because of medication does not understand, and even serve this dose for 248 days, to August 15, occurred only in soft palsy medicine. At that time, the total dose of gossypol 4.96g. Patients began to have fatigue in July, numbness and other limbs, the day of onset woke up and found that both lower extremities can not move, unable to stand up, that is carried to our hospital emergency room. Physical examination found that limb muscle tension decreased significantly, lower extremity muscle strength of 1 to 2, 2 to 3 upper limb muscle strength. There was no obvious disturbance in the abdomen and knee, disappearance of knee reflex, weakened Achilles tendon reflexes, crest reflexes and pathological reflexes (1); serum potassium 1.9mEg / L; each u wave of electrocardiogram significantly, V_1-V_4Tu fusion u = T, IV_4 T wave low flat, in line with hypokalemia. Patients before taking the physical examination, normal ECG, serum potassium 4.6mEg / L. No previous history of a similar attack and family history, immediately diagnosed as hypokalemic paralysis, giving potassium treatment, three days after the patient’s limb activity gradually restored, you can walk under the ground,