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1954年施莱尔(Schleyer)发表了关于尸体血清的蛋白纸上电泳的系统研究结果。他主要是从死后血清蛋白谱发生变化的问题出发,研究了这种变化是否与尸体时间有关,以及能在多大程度上推断死前情况。由于死后取样时间的不同,随着球蛋白的严重分散加剧,白蛋白的成分一般要减少到活体血值的一半。贝内克(Beneke)和巴恩(Bahn,1961)曾认为分子较小的白蛋白向血管外渗出与此有关。1962年罗宾逊(Robinson)和凯伦贝尔格(Kellenberger)公布的有关生前和死后血的比较研究,也是使用纸上电泳法对蛋白进行分离的。他们发现,死后血比活体血在β球蛋白范围内出现较
In 1954, Schleyer published a systematic study on the electrophoresis of protein on body serum. He mainly started from the issue of changes in the serum protein profile after death, examining whether the change is related to the time of the body and to what extent the pre-mortem can be inferred. Due to the difference in sampling time after death, the composition of albumin is generally reduced to about half the blood value of the living body as the severity of the globulin is exacerbated. Beneke and Bahn (1961) have argued that extracorporeal leakage of smaller molecules of albumin is associated with this. A comparative study of prenatal and post-mortem blood published by Robinson and Kellenberger in 1962 also separated the protein using on-paper electrophoresis. They found that post-mortem blood appeared more than beta-globulin in living blood