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津NP_9栓经多中心临床342例3963个月经周期的观察避孕有效率99.07％/百妇年,对照组美国Intercent栓116例,1296个月经周期有效率98.17/百妇年,两组比较无显著性差异(x=0.58,P>0.05)。副反应除外阴搔痒外,分泌物增多、阴道烧灼感和男方局部不适两组有显著性差异(P<0.01)。提出:津NP_9栓副反应少于Intercept栓。使用不当是失败的主要原因,78.3％的失败致孕者发生在用药头4个月,因此指导正确使用方法是提高避孕效率的不可缺少的因素。
Jin NP_9 by the multi-center clinical 342 cases of 3963 menstrual cycle observation contraceptive efficiency of 99.07% / hundred years, the control group of Interinter 116 cases, 1296 menstrual cycle efficiency of 98.17 / hundred years, the two groups were insignificant Sex differences (x = 0.58, P> 0.05). Side effects in addition to genital itching, secretions increased, vaginal burning sensation and men’s discomfort were significantly different between the two groups (P <0.01). Proposed: Jin NP_9 bolt less side effects than Intercept suppository. Improper use is the main reason for the failure. 78.3% failed pregnancies occurred in the first 4 months of medication. Therefore, guiding proper use is an indispensable factor in improving contraceptive efficiency.