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1973年3月我们开始在附属医院门诊应用负压吸引方法,进行鼻咽脱落细胞学诊断的研究,至1974年初对120例病例做了总结。此后,在方法上进行了一些改进,并在参加五官科门诊的医务人员及进修生中普遍推广使用,也用于徐闻县下洋及前山两公社的普查,以探索本方法普及使用的情况。至1976年10月在门诊共进行负压吸引脱落细胞学检查789例,其中鼻咽癌患者共458例。细胞学及活检均为阳性者380例;活检阴性、细胞学阳性者25例(其中12例经第二次活检确诊为鼻咽癌;13例患者未进行第二次活检,但鼻咽腔有明显肿物,伴有颈淋巴结肿大或颅神经损害);活检阳性、细胞学阴性者53例。脱落细胞学诊断符合率为88.4%,活检为94.3%。现分别就负压吸引方法及细胞学诊断价值两方面进行总结,以探讨脱落细胞学检查作为鼻咽癌常规诊断检查的可能性。
In March 1973, we began to use the method of vacuum suction in the outpatient department of the affiliated hospital for the study of cytological diagnosis of nasopharyngeal exfoliation. We summarized the 120 cases in early 1974. Since then, some improvements have been made in the method. They have been widely promoted among medical personnel and scholars participating in the ENT clinics, and also used in the census of the Xigong and Qianshan Communes in Xuwen County to explore the widespread use of this method. By the end of October 1976, a total of 789 cases of negative pressure suction and cytological examinations were performed in outpatients, of which 458 were nasopharyngeal carcinoma patients. There were 380 cases with positive cytology and biopsy; 25 cases with negative biopsy and positive cytology (12 cases were diagnosed as nasopharyngeal carcinoma after the second biopsy; 13 cases had no second biopsy, but the nasopharyngeal cavity had Significant mass with cervical lymph node enlargement or cranial nerve damage; 53 cases with positive biopsy and negative cytology. The diagnostic coincidence rate of exfoliated cytology was 88.4% and biopsy was 94.3%. The two aspects of vacuum suction method and cytology diagnostic value are summarized separately to explore the possibility of exfoliative cytology as a routine diagnostic test for nasopharyngeal carcinoma.