兹将我院收治两例阵发性睡眠性血红蛋白尿(PNH)并发血栓性 DIC 报道如下.例一:女,24岁,住院号250856。7个月前因发热、腰痛、酱油尿,经 Ham 试验诊为 PNH.2月前娩一死婴,流血不多,低热,给抗生素治疗,热退。住院20天前 PNH 复发,伴头痛、呕吐,两次颅压均高(330、550mmH_2O),但脑脊液常规及生化正常。四肢皮肤可见数片出血斑,贫血貌,巩膜轻度黄染,左下肢高度凹陷性浮肿,股静脉处有压痛,足背动脉存在,左下肢肌力、生理反射减弱。病理反射未引出. Here are two cases of paroxysmal nocturnal hemoglobinuria (PNH) in our hospital complicated with thrombotic DIC are reported as follows.Example I: Female, 24 years old, hospitalization 250856.7 months ago due to fever, back pain, soy sauce urine, after Ham Test diagnosis of PNH.2 months before delivery a clinical, less bleeding, fever, antibiotic treatment, thermal withdrawal. PNH recurrence 20 days before admission, with headache, vomiting, both intracranial pressure were high (330,550mmH_2O), but routine and biochemical CSF normal. Extremity skin can be seen several pieces of bleeding spots, anemia appearance, scleral mild yellow dye, left lower extremity highly depressed edema, tenderness at the femoral vein, dorsalis pedis artery exists, left lower extremity muscle strength, decreased physiological reflex. Pathological reflex did not lead.