论文部分内容阅读
84例经组织学或细胞学证实的晚期食管癌接受铂类及氟脲嘧啶联合化疗后再予以放疗。近期疗效显示完全缓解28.5％,部分缓解51.2％,总有效率为79.7％。1、2、3年生存率分别为60.7％、41.7％和25.0％。结果还表明食管癌的远期生存与食管癌的部位及有无锁骨上淋巴结转移有关,而病变长度与远期生存率无显著差异。故认为在放疗前加用联合化疗以防止远处转移或抑制已播散的亚临床转移,可以提高晚期食道癌的生存率。
Eighty-four cases of advanced esophageal cancer confirmed by histology or cytology were treated with platinum and fluorouracil combined with chemotherapy followed by radiotherapy. The recent curative effect showed a complete remission of 28.5%, a partial remission of 51.2%, and a total effective rate of 79.7%. The 1-, 2-, and 3-year survival rates were 60.7%, 41.7%, and 25.0%, respectively. The results also showed that the long-term survival of esophageal cancer was related to the location of esophageal cancer and the presence or absence of supraclavicular lymph node metastasis. There was no significant difference in the length of lesions and long-term survival. Therefore, it is considered that the use of combination chemotherapy before radiotherapy to prevent distant metastasis or to suppress disseminated subclinical metastases can improve the survival rate of advanced esophageal cancer.