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[目的]探讨莫沙必利对胶囊内镜检查质量的影响。[方法]将55例进行胶囊内镜检查的患者随机分为研究组(27例)和对照组(28例)。研究组检查前晚和服用胶囊内镜前30min各口服莫沙必利5mg,对照组则不服任何药物。观察2组患者在肠道准备中有无恶心、呕吐、腹痛等不良反应,记录2组患者胶囊内镜在胃内和小肠的运行时间、排出体内时间和图像评分并进行比较。[结果]研究组在肠道准备过程中不良反应发生率、胶囊内镜胃内运行时间明显低于对照组(P<0.05),图像评分明显高于对照组(P<0.05);2组胶囊内镜小肠内运行时间比较差异无统计学意义(P>0.05)。[结论]莫沙必利能明显减少胶囊内镜检查肠道准备过程中的不良反应和胶囊内镜胃排空时间,提高肠道清洁度及图像质量,安全性高。
[Objective] To investigate the influence of mosapride on the quality of capsule endoscopy. [Methods] 55 patients with capsule endoscopy were randomly divided into study group (27 cases) and control group (28 cases). In the study group, mosapride 5 mg was orally administered 30 min before the evening of the test and before capsule administration, while the control group was not given any medication. Two groups of patients in the intestine preparation were observed for nausea, vomiting, abdominal pain and other adverse reactions, capsule endoscopy in two groups of patients running time in the stomach and small intestine, body time and image scores were discharged and compared. [Results] The incidence of adverse reactions in the study group during the process of bowel preparation was significantly lower than that of the control group (P <0.05), the image score was significantly higher than that of the control group (P <0.05) There was no significant difference in the running time of endoscopic small intestine (P> 0.05). [Conclusion] Mosapride can significantly reduce the adverse reactions during capsule endoscopy in the process of bowel preparation and the time of gastric emptying in capsule endoscopy, and improve the intestinal cleanliness and image quality with high safety.