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目的探讨痰热清注射液治疗呼吸机相关性肺炎的应用效果。方法选取2012年1月至2014年1月我院治疗的呼吸机相关性肺炎患者74例,采用单双号法将其分为两组,对照组患者行常规治疗,观察组患者在常规治疗的基础上采用痰热清注射液治疗,观察两组患者的退临床疗效以及C-反应蛋白(CRP)水平的变化情况。结果观察组治疗有效率为97.3%,明显高于对照组的73.0%,差异有统计学意义(P<0.05)。治疗前两组患者的CRP水平比较,差异无统计学意义(P>0.05),治疗后观察组患者的CRP水平明显低于对照组,差异有统计学意义(P<0.05)。观察组患者的机械通气时间和重症监护病房(ICU)监护时间明显少于对照组,差异有统计学意义(P<0.05)。结论采用痰热清注射液治疗呼吸机相关性肺炎,能有效控制疾病发展,同时可抑制炎性反应的发生。
Objective To investigate the effect of Tanreqing Injection in the treatment of ventilator-associated pneumonia. Methods Seventy-four patients with ventilator-associated pneumonia treated in our hospital from January 2012 to January 2014 were divided into two groups according to the single and double number method. The patients in the control group were treated routinely and the patients in the observation group received routine treatment On the basis of Tanreqing injection, the clinical effect and C-reactive protein (CRP) level in both groups were observed. Results The effective rate of the observation group was 97.3%, which was significantly higher than that of the control group (73.0%), the difference was statistically significant (P <0.05). There was no significant difference in CRP levels between the two groups before treatment (P> 0.05). After treatment, the CRP level in the observation group was significantly lower than that in the control group (P <0.05). The duration of mechanical ventilation and intensive care unit (ICU) monitoring in the observation group were significantly less than those in the control group, with significant differences (P <0.05). Conclusion Tanreqing injection in the treatment of ventilator-associated pneumonia can effectively control the disease development, and can inhibit the occurrence of inflammatory reactions.