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大兴安岭地区,气候寒冷,日照时间短,皮肤暴露的面积小,佝偻病的发病率很高。单纯母乳喂养增加辅食不能满足婴儿维生素D的需要,100毫升母乳仅含维生素D0.4-10单位。所以,为了预防佝偻病,从新生儿期开始投给维生素D到一岁为止。关于用量问题尚有争议。我们认为每日投给生理需要的维生素D效果较好。每日摄取量34-168单位.增加到400-600单位,平均400单位。维生素D来源于人工配方奶粉每100克奶粉含维生素D400单位。奶粉与维生素D的量与婴儿年龄,体重增长成正比。通过对50例人工配方奶粉喂养婴儿观察,应用上述剂量可以预防佝偻病,去发现中毒症状。按每日400单位维生素D计算,一年总量为146.000单位约为一次突击疗法40万单位的1/3;反之,一次性用量等于400单位(每日)三年的总用量。突击疗法间隔一个月,连用三次,总量120万单位,此量是否太大,血清中25(OH)D能维持多久,值得探讨。
Daxinganling area, cold weather, short sunshine time, skin exposed area is small, the incidence of rickets is high. Supplement breastfeeding alone can not meet the needs of infant vitamin D, 100 ml of breast milk contains only vitamin D0.4-10 units. Therefore, in order to prevent rickets, from the beginning of the newborn to vitamin D until the age of one. There is still controversy about the dosage. We think that daily administration of vitamin D for physiological needs is better. Daily intake of 34-168 units. Increased to 400-600 units, an average of 400 units. Vitamin D derived from artificial milk formula every 100 grams of milk contains vitamin D400 units. The amount of milk powder and vitamin D and infant age, weight gain is proportional to. Through the observation of 50 cases of infant formula fed with artificial milk formula, the above dosage can prevent rickets and find symptoms of poisoning. Calculated on a daily basis of 400 units of vitamin D, a total of 146.000 units a year is about one-third of the one-off assault treatment of 400,000 units; on the contrary, the one-time dosage is equal to 400 units (daily) total amount of three years. Assault therapy interval of one month, three times in a row, the total amount of 1200000 units, the amount is too large, serum 25 (OH) D can maintain how long, it is worth exploring.