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丙型肝炎属于黄病毒家族的E链RNA病毒。HCV感染的最大特点是极易演变为慢性。且病情有逐步加重的趋势。目前有少数学者在研究丙型肝炎发病机理时,证实了外周血单个核细胞中存在HCV RNA。为进一步探讨患者不明原因ALT升高、查找病原学,我们将细胞内检测HCV RNA技术用于临床,对疑为丙型肝炎的患者同步检测血浆及外周血单个核细胞中HCV RNA,现报道如下。 1 材料与方法
Hepatitis C belongs to the flavivirus family E-chain RNA virus. The most prominent feature of HCV infection is that it can easily become chronic. And the condition has gradually increased the trend. At present, a few scholars have confirmed the presence of HCV RNA in peripheral blood mononuclear cells when studying the pathogenesis of hepatitis C. To further investigate patients with unexplained ALT elevation and to search for etiology, we used intracellular detection of HCV RNA in clinical trials, and simultaneous detection of HCV RNA in plasma and peripheral blood mononuclear cells in patients with suspected hepatitis C is reported below . 1 materials and methods