论文部分内容阅读
目的:观察对以泊路沙姆为助溶剂的脉络宁新注射液(P-脉络宁)对缺血性脑损伤的保护作用.方法:测定P-脉络宁注射液对不同缺血模型及血液流变学的作用.结果:脉络宁注射液能明显降低家兔的全血比粘度;血浆比粘度及红细胞比容;并能明显缩小小鼠大脑中动脉阻断(MCAO)后引起的脑梗死范围,降低毛细血管通透性、脑含水量和脑指数.结论:P-脉络宁可以通过改善上述各指标,有效地保护缺血引起的脑损伤;而助溶剂则无此脑保护作用.
OBJECTIVE: To observe the protective effect of Mailuoningxin injection (P-Mailuoning), a nebulizing agent of shampoo, on ischemic brain injury.METHODS: The effect of P-Mailuoning injection on ischemia model and blood Rheumatic effect.Results: Mailuoning injection can significantly reduce rabbit whole blood viscosity; plasma specific viscosity and hematocrit; and can significantly reduce the mouse middle cerebral artery occlusion (MCAO) caused by cerebral infarction Range, decreased capillary permeability, brain water content and brain index.Conclusion: P-Mailuoning can effectively protect the brain from ischemic injury by improving the above indexes;