过去都认为支气管哮喘的发作是由于支气管痉挛。然而,支气管痉挛并非最显著的病理改变,本病肺部最突出的病理变化是在支气管和毛细支气管管腔内存在着粘液栓子。其他病变包括支气管粘膜和粘膜下水肿、支气管管腔内有柱状上皮细胞的脱落、粘膜下层毛细血管扩张、肥大细胞脱颗粒、嗜酸性粒细胞浸润和支气管粘膜的基底膜增厚。 In the past that the onset of bronchial asthma is due to bronchospasm. However, bronchospasm is not the most prominent pathological change. The most prominent pathological change in the lungs of this disease is the presence of mucinous emboli in the bronchial and bronchiolar lumen. Other lesions include bronchial mucosa and submucosal edema, shedding of columnar epithelial cells in the bronchial lumen, telangiectasias in the submucosa, degranulation of mast cells, eosinophilic infiltration and thickening of the bronchial mucosa.