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目的分析手足口病患儿实施免疫球蛋白与超敏C反应蛋(hs-CRP)检测的临床意义。方法 62例健康儿童作为对照组,62例手足口病患儿作为实验组,对其进行免疫球蛋白、hs-CRP检测。结果实验组外周血IgA水平较对照组显著降低(P<0.05),IgG明显降低(P<0.05),IgM无明显差异(P>0.05);实验组hs-CRP明显高于对照组(P<0.05)。结论充分重视检测免疫球蛋白与hs-CRP指标变化,可为手足口病诊治工作提供参考依据。
Objective To analyze the clinical significance of detection of immunoglobulin and hs-CRP in children with hand-foot-mouth disease. Methods Sixty-two healthy children served as the control group and 62 children with hand-foot-mouth disease as experimental group. Immunoglobulin and hs-CRP were detected. Results The level of IgA in experimental group was significantly lower than that in control group (P <0.05), IgG was significantly lower (P <0.05), IgM was not significantly different (P> 0.05); hs-CRP in experimental group was significantly higher than that in control group 0.05). Conclusion The importance of detection of immunoglobulin and hs-CRP index changes may provide a reference for the diagnosis and treatment of HFMD.