角膜软化症是维生素A缺乏引起角膜、结膜上皮干燥变性 ,晚期出现角膜混浊、软化、溃疡、坏死、穿孔而失明 ,常双眼发病。解放前为小儿致盲的主要眼病之一 ,解放后随着人民生活水平提高 ,角膜软化症的发病率大大降低 ,近年来报道不多。作者于 1 994年 1月至 2 0 0 0年 8月共收治 Corneal softening is caused by a lack of vitamin A cornea, conjunctival epithelial dry degeneration, corneal opacification late, softening, ulcers, necrosis, perforation and blindness, often both eyes. Before the liberation of one of the main eye diseases in children with blinding, with the improvement of people’s living standards after liberation, the incidence of corneal softening greatly reduced, reported in recent years small. The author from January 1994 to August 2000 were admitted