米托蒽醌(mitoxantrone)是新的蒽醌类抗癌药,对转移性乳癌有效率约20-30％,其毒性低。 本文报告作者在1984.2-1985.3收集的32例晚期或转移性乳癌,用米托蒽醌加环磷酰胺治疗的结果。 资料与方法 治疗前白细胞数均须大于4000/mm~3,血小板计数大于10万/mm~3,血胆红素及血肌酐值小于2.0mg％,并作胸部X线,骨和肝同位素扫描检查,肝肾功能,心电图及一般状况等检查 Mitoxantrone is a new antitumor antitumor drug with an efficacy of about 20-30% for metastatic breast cancer, and its toxicity is low. This article reports the results of mitoxantrone plus cyclophosphamide in 32 cases of advanced or metastatic breast cancer collected by the author on 1984.2-1985.3. Materials and Methods The number of leukocytes before treatment must be greater than 4000/mm~3, platelet count greater than 100,000/mm~3, blood bilirubin and serum creatinine value less than 2.0mg%, and chest X-ray, bone and liver isotope scans Examination, liver and kidney function, electrocardiogram and general condition examination