髓外原发性浆细胞瘤多见于呼吸道和消化道。颅内原发性孤立性浆细胞瘤十分罕见。French氏1947年最先报告1例丘脑下部的浆细胞瘤,以后直至1971年,文献上仅有6例报道。1979年中山医学院,在964例中枢神经系统肿瘤病理统计材料中仅有2例,1例肿瘤位于硬脑膜,1例肿瘤位于颈脊膜外。最近我们遇到1例,发生于椎管内,现将此例报道如下: Extramedullary primary plasmacytoma more common in the respiratory tract and digestive tract. Intracranial primary solitary plasmacytoma is very rare. In 1947, French’s first report of a plasmacytoma in the lower part of the hypothalamus was reported in only 6 cases in the literature up to 1971. Zhongshan Medical College in 1979, 964 cases of central nervous system tumor pathology statistical material only 2 cases, 1 case of tumor located in the dura mater, 1 case of tumor located outside the cervical membrane. We recently encountered a case occurred in the spinal canal, now this case is reported as follows: