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增殖性玻璃体视网膜病变(PVR)是当前眼科界进展很快的一个热门课题。对视网膜色素上皮(RPE)和神经胶质细胞增殖性病理过程的了解,为治疗此病提供理论根据。玻璃体手术可以切除玻璃体内以及视网膜前后表面的增生组织,加上视网膜切开术和固定术,以气体或硅油作眼内填塞,已使严重PVR病例的手术成功率达到75%。应用药物抑制细胞增生能进一步减少复发,提高成功率。
Proliferative vitreoretinopathy (PVR) is the current progress of the ophthalmic industry is a hot topic. Understanding of the proliferative pathological processes of RPE and glial cells provides a theoretical basis for the treatment of this disease. Vitrectomy removes vitreous as well as proliferative tissue on the anterior and posterior retinal surfaces. Retinal incision and fixation with gas or silicone oil for intra-ocular filling has resulted in a 75% success rate in severe PVR. Application of drugs to inhibit cell proliferation can further reduce the recurrence and improve the success rate.