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研究活性氧在油酸型成人呼吸窘迫综合征（ARDS）发病中的作用及维生素E（VE）的保护作用。结果表明，油酸组肺组织和血浆内丙二醛（MDA）含量及BALF蛋白含量增加显著（P＜o．05）；全血谷胱甘肽过氧化物酶和血浆铜蓝蛋白活性及PO2。显著降低（P＜0．05）;VE治疗组损伤轻油酸组明显减轻（P＜0．05）。此外，PO2与肺组织内MDA含量之间具有良好的线性关系。提示活性氧可促使油酸型ARDS的发病，VE具有显著保护作用。
To study the role of reactive oxygen species (ROS) in the pathogenesis of oleic acid-induced adult respiratory distress syndrome (ARDS) and the protective effect of vitamin E (VE). The results showed that the content of malondialdehyde (MDA) and the content of BALF protein in lung tissue and plasma of oleic acid group increased significantly (P <0.05); the activity of glutathione peroxidase and ceruloplasmin in whole blood and PO2 . (P <0.05). In VE treatment group, the light oleic acid group was significantly reduced (P <0.05). In addition, there is a good linear relationship between PO2 and MDA content in lung tissue. Tip reactive oxygen species can promote the incidence of oleic ARDS, VE has a significant protective effect.