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目的探讨血清(D-二聚体)在急性肺栓塞(PE)患者中的临床价值。方法用免疫比浊法检测急性PE患者42例和对照组20例血清D-二聚体水平。结果肺栓塞组血清D-二聚体水平(1.71±0.86)mg/L显著高于对照组(0.29±0.14)mg/L,差异有统计学意义(P<0.05)。D-二聚体阳性率为92.1%,D-二聚体诊断PE的敏感性为93.0%,特异性为69.7%。结论用免疫比浊法测定D-dimer可作为PE的敏感、快速、廉价的初步筛选指标,值得在急诊临床中推广应用。
Objective To investigate the clinical value of serum (D-dimer) in patients with acute pulmonary embolism (PE). Methods The levels of serum D-dimer in 42 cases of acute PE and 20 cases of control group were detected by immunoturbidimetry. Results The level of D-dimer (1.71 ± 0.86) mg / L in pulmonary embolism group was significantly higher than that in control group (0.29 ± 0.14) mg / L, the difference was statistically significant (P <0.05). The positive rate of D-dimer was 92.1%, the sensitivity of D-dimer to diagnose PE was 93.0% and the specificity was 69.7%. Conclusion Immunoturbidimetry D-dimer can be used as a sensitive, rapid and inexpensive primary screening index for PE, which is worthy of promotion and application in the emergency clinic.