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目的:探讨地塞米松、葡萄糖酸钙、米索联合卡前列素氨丁三醇注射液防治高危妊娠产妇产后出血的临床效果及安全性。方法 :选取2013年1月~2015年1月期间我院收治的高危妊娠产妇140例为研究对象,按照随机数字表法分为观察组(n=70)与对照组(n=70),给予对照组产妇地塞米松、葡萄糖酸钙及米索治疗,观察组在对照组治疗基础上,加用卡前列素氨丁三醇注射液,剖宫产产妇子宫体肌肉注射、阴道分娩产妇分娩后行臀部肌肉注射,比较两组产妇分娩前后SBP、DBP、HR及产后出血量。结果:治疗后,观察组SBP、SBP及HR指标明显优于对照组,差异明显(P<0.05);观察组出血量明显少于对照组,且不良反应发生率明显低于对照组,差异明显具有统计学意义(P<0.05)。结论 :防治高危妊娠产妇产后出血,联合用药的效果明显,安全性高,值得在临床上进一步推广应用。
Objective: To investigate the clinical effects and safety of dexamethasone, calcium gluconate and misoprostol-carboprost in the prevention and treatment of postpartum hemorrhage in high-risk pregnancy. Methods: One hundred and forty cases of high-risk pregnant women who were admitted to our hospital from January 2013 to January 2015 were selected as research object. According to random number table, the patients were divided into observation group (n = 70) and control group (n = 70) Control group maternal dexamethasone, calcium gluconate and misoprostol treatment group in the control group based on the treatment, plus carboprost trometamol injection, cesarean section uterine body intramuscular injection, vaginal delivery maternal delivery Line intramuscular injection of buttocks, before and after delivery of two groups of maternal SBP, DBP, HR and postpartum hemorrhage. Results: After treatment, the SBP, SBP and HR indexes of the observation group were significantly better than those of the control group (P <0.05); the bleeding volume of the observation group was less than that of the control group, and the incidence of adverse reactions was significantly lower than that of the control group Statistically significant (P <0.05). Conclusion: The prevention and treatment of postpartum hemorrhage in pregnant women with high risk pregnancy has obvious effect of combination therapy and high safety, so it is worth further clinical application.