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按Murnhy法制成老化红细胞模型，利用丝裂原激活的小鼠脾细胞方法测定T淋巴细胞白细胞介素2（IL－2）的分泌水平．结果表明：5×105／ml、105／ml、5×105／ml老化细胞对T淋巴细胞IL－2水平有明显的提高作用（分别为P＜0．05、P＜0．01和P＜0．01）．经过丹酚酸B5μg、15m，知母宁5μg、15μg温育后的老化红细胞对T淋巴细胞IL－2分泌有明显的影响，其中丹酚酸B5μg、15μg，知母宁15μg有明显的提高作用（P＜0．01），而知母宁5μg作用不明显（P＞0．05）．表明丹酚酸B、知母宁能增强老化红细胞提高T淋巴细胞分泌IL－2．
According to the Murnhy method, an aging erythrocyte model was made, and the secretion of interleukin 2 (T-lymphocyte) by T lymphocyte was determined by using mitogen-activated mouse spleen cells. The results showed that 5 × 105 / ml, 105 / ml and 5 × 105 / ml of aging cells significantly increased IL-2 level in T lymphocytes (P <0.05, P <0.01 and P < 0.01). After salvianolic acid B5μg, 15m, Zhimu Ning 5μg, 15μg after incubation of aging erythrocytes on T lymphocytes IL-2 secretion had a significant effect, including salvianolic acid B5μg, 15μg, Zhuningning 15μg significantly improved (P <0.01), while Zhuningning 5μg had no significant effect (P> 0.05). Show that salvianolic acid B, Zhimu Ning can enhance the aging of red blood cells to enhance the secretion of IL-2 by T lymphocytes.