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目的:观察加味当归补血汤联合左卡尼汀治疗少弱精子症的临床疗效。方法:将60例少弱精子症患者随机分为2组各30例,对照组口服左卡尼汀,多维元素(29);治疗组在对照治疗的同时加服用加味当归补血汤。观察临床疗效及治疗前后精液分析各项指标。结果:2组治疗后精子密度、精子活动率、精子活力分别与治疗前比较,差异均有非常显著性意义(P<0.01);治疗组精子密度、精子活力a级、精子活力a+b级改善均优于对照组,差异均有非常显著性意义(P<0.01);精子活动率治疗组治疗后改善优于对照组,差异有显著性意义(P<0.05);总有效率治疗组90.0%,对照组73.3%,2组疗效比较,差异有显著性意义(P<0.05)。结论:左卡尼丁能提高精子的密度、活动率及活力,用药安全,对治疗少弱精子症有良好的临床疗效,联合加味当归补血汤治疗效果更明显,两者有协同作用。
Objective: To observe the clinical effect of Modified Dangguibuxuetang combined with levocarnitine in the treatment of oligoasthenospermia. Methods: Sixty patients with oligoasthenospermia were randomly divided into two groups of 30 patients. The control group was treated with L-carnitine and multi-dimensional elements (29). The treatment group was given Jiawei Dangguibuxuetang at the same time. To observe the clinical efficacy and semen analysis before and after treatment of various indicators. Results: There was significant difference in sperm concentration, sperm motility and sperm motility between the two groups before and after treatment (P <0.01). The sperm density, a-sperm motility, a + b sperm motility (P <0.01); sperm motility rate in treatment group was better than that in control group, the difference was significant (P <0.05); total effective rate in treatment group was 90.0 %, 73.3% in the control group, the difference between the two groups was significant (P <0.05). Conclusion: Zuccarenin can improve sperm density, activity and vitality, medication safety, for the treatment of oligoasthenosus syndrome has a good clinical effect, combined with Modified Dangguibuxue Decoction treatment effect is more obvious, the two have synergistic effects.