【摘 要】
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Dear Editor,The homeostasis of the central nervous system (CNS) is regulated through the blood-brain barrier (BBB),a protective barrier between the peripheral b
【机 构】
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Key Laboratory of Protein and Peptide Pharmaceutical, Institute of Biophysics, Chinese Academy of Sc
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Dear Editor,The homeostasis of the central nervous system (CNS) is regulated through the blood-brain barrier (BBB),a protective barrier between the peripheral blood and the brain (Zhao et al.,2015).As vascular mural cells of brain microvessels,pericytes are positioned within the neurovascular unit among endothelial cells (ECs),astrocytes,and neurons.During the embryogenesis,pericytes are recruited to and interacts with the nascent CNS vascular ECs for BBB formation and maturation.The recruitment of pericytes to CNS vessels is hence critical for BBB development.
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