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目的探讨糖代谢异常患者冠状动脉病变的特点。方法 168例行冠脉造影证实冠心病患者分为单纯冠心病组(NGT组),冠心病合并糖尿病组(DM组)40,冠心病合并糖耐量异常组(IGT组)45例。所有患者均检测血糖采用口服葡萄糖耐量试验(OGTT)作为评估糖代谢的标准。对其冠状动脉的病变程度及狭窄程度进行分析。结果糖尿病组中冠状动脉病变侵犯左主干和前降支的比例高,发病年龄较血糖正常组低,糖尿病组和糖耐量异常组的冠状动脉病变中多支病变和重度病变发生率高(P<0.05),单支病变发生率较低(P<0.05)。结论糖尿病及糖耐量异常合并冠心病患者冠状动脉病变广泛且严重。
Objective To investigate the characteristics of coronary artery lesions in patients with abnormal glucose metabolism. Methods 168 coronary angiography confirmed coronary heart disease patients were divided into simple coronary heart disease group (NGT group), coronary heart disease with diabetes mellitus (DM group) 40, coronary heart disease with impaired glucose tolerance group (IGT group) 45 cases. Blood glucose was measured in all patients. Oral glucose tolerance test (OGTT) was used as a standard for assessing glucose metabolism. The extent of coronary lesions and stenosis were analyzed. Results The prevalence of coronary lesions in the diabetic group was higher than that in the left main and anterior descending branches, and the age of onset was lower than that of the normal group. The incidence of multi - vessel disease and severe coronary artery disease in the diabetic group and the impaired glucose tolerance group were higher (P < 0.05), single vessel disease was lower (P <0.05). Conclusion Diabetic and impaired glucose tolerance in patients with coronary heart disease coronary lesions extensive and serious.