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口服避孕药(oral contraceptives,以下简称避孕药)是在肝脏进行生物代谢的药物,由于肝细胞对性激素很敏感,易造成肝细胞损伤,导致肝内胆汁郁积、Budd-Chiari 综合征、胆囊炎和胆石症、肝脏良性肿瘤及恶性肿瘤。但各家对避孕药与肝脏肿瘤关系的报道极不一致。因此,有必要对这个问题作进一步阐明。一、避孕药与局灶性结节增生目前关于局灶性结节增生(focal nodularhyperplasia,FNH)的性质尚未定论,有人认
Oral contraceptives (or contraceptives) are biometabolism drugs in the liver. Because liver cells are sensitive to sex hormones, they are likely to cause liver cell damage, resulting in intrahepatic cholestasis, Budd-Chiari syndrome, cholecystitis and Cholelithiasis, benign liver tumors and malignant tumors. However, reports on the relationship between contraceptives and liver tumors are extremely inconsistent. Therefore, it is necessary to further clarify this issue. 1. The nature of focal nodular hyperplasia (FNH) of contraceptives and focal nodular hyperplasia is currently inconclusive.