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目的分析深圳市南山区美沙酮维持治疗门诊接受治疗者HIV、HCV和梅毒等血源性传染病的感染状况,为采取针对性干预措施提供依据。方法收集深圳市南山区美沙酮门诊2008年至2013年7月间收治的303名吸毒者的资料,采用描述性流行病学方法分析受治者的人口学特征、感染状况和不同特征之间感染率的差异。结果南山区美沙酮维持治疗门诊受治者中73.88%(198/268)的受治者至少感染HIV、HCV和梅毒3种病毒中的1种,其中HIV的感染率为5.26%(14/266)、HCV的感染率为70.72%(186/263)、梅毒的感染率为7.34%(19/259)。HIV和HCV双重感染率为3.82%(10/262),HIV和梅毒双重感染率为0.39%(1/259),HCV与梅毒双重感染率为4.28%(11/257)。HIV感染率在不同吸毒方式、是否共用注射器、不同文化程度和婚姻状况等特征受治者之间差异均有统计学意义(P<0.05或P<0.01),以注射吸毒(11.4%)和共用注射器者(66.7%)以及小学或文盲者(11.8%)、未婚者(9.2%)HIV感染率较高。HCV感染率在不同吸毒方式之间差异有统计学意义(P<0.01),其中注射吸毒者阳性率最高为88.6%(70/79)。梅毒感染率在不同人口学特征之间差异均无统计学意义(均P>0.05)。结论深圳市南山区美沙酮门诊接受治疗者HIV、HCV和梅毒感染率略高于广东省平均水平,合并感染率较高,对该人群应加强HCV和梅毒的筛查,积极开展感染者转诊治疗和行为干预。
Objective To analyze the infection status of blood-borne infectious diseases such as HIV, HCV and syphilis among the methadone maintenance treatment clinics in Nanshan District of Shenzhen City, so as to provide the basis for taking targeted interventions. Methods The data of 303 drug abusers who were admitted to methadone clinics in Nanshan District of Shenzhen from 2008 to July 2013 were collected. The demographic characteristics, infection status and infection rates among different characteristics of the subjects were analyzed by descriptive epidemiological method The difference. Results 73.88% (198/268) of the recipients of methadone maintenance treatment outpatient in Nanshan District were infected with at least one of the three viruses of HIV, HCV and syphilis, and the infection rate of HIV was 5.26% (14/266) , The infection rate of HCV was 70.72% (186/263) and the infection rate of syphilis was 7.34% (19/259). The rates of HIV and HCV infection were 3.82% (10/262), those of HIV and syphilis were 0.39% (1/259) and those of HCV and syphilis were 4.28% (11/257) respectively. HIV infection rates were significantly different between drug abusers, syringes sharing, education level and marital status (P <0.05 or P <0.01), and drug abuse (11.4%) and sharing Syphilis (66.7%) and primary or illiterate (11.8%), unmarried (9.2%) had a higher rate of HIV infection. The prevalence of HCV infection among different drug abusers was statistically significant (P <0.01), of which the highest positive rate was 88.6% (70/79). There was no significant difference in syphilis infection rate between different demographic characteristics (all P> 0.05). Conclusion The prevalence of HIV, HCV and syphilis in methadone clinics in Nanshan District of Shenzhen City was slightly higher than that of Guangdong Province with a high rate of co-infection. HCV and syphilis screening should be strengthened in this population, and positive referrals And behavioral interventions.