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为揭示导致慢性渗出性中耳炎的发病因素,作者们分别用①1%角叉菜钙胶(calcium carrageenin),②辣根过氧化物酶(H R P)特异免疫复合溶液,③HR P单纯溶液。三种致炎剂注入100只试验鼠的中耳腔内,做了鼓室压图(TG)变化及病理组织学观察。发现1%角叉菜钙胶注入后6小时,TG的声顺和梯度下降,3～4天后迅速恢复正常。H R P特异免疫复合溶液注入6小时,其声顺值缓慢下降,12小时后下降更明显,TG几乎接近B型,约持续6天后过渡至C型,至少需14天TG方能恢复至A型。HR P单纯溶液注入后,迅速出现声顺值下降,
To reveal the pathogenesis of chronic exudative otitis media, the authors used ① 1% calcium carrageenin, ② HRP specific immune complex solution, ③ HRP simple solution. Three kinds of inflammatory agents were injected into the middle ear cavity of 100 rats, and tympanogram (TG) and histopathology were observed. Found 6% carrageenan 1% carrageenan injection, TG sound and gradient decline, 3 to 4 days quickly returned to normal. H R P-specific immune complex solution injected 6 hours, the sound decline slowly decreased, more obvious after 12 hours decline, TG nearly B-type, about 6 days after the transition to C-type, at least 14 days TG can return to A-type. HR P simple solution injection, the rapid decline in acoustic compliance,