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目的:通过对本院2 995例无创臂踝脉搏波传导速度(baPWV)和踝臂血压指数(ABI)检测结果的分析,探讨动脉粥样硬化早期无创检测技术在健康体检中应用的意义。方法:选择2010-07-2011-02在本院健康体检的人员进行检测,年龄在25～85岁,按5年间隔的年龄分段,测量并分析baPWV和ABI与其他物理和生化指标的相关性。结果:无论男性或是女性的体检人群中,baPWV平均值以及异常检出率随着年龄增长而有所增加,而且年龄对baPWV的影响系数,女性比男性要大。在45～54岁之间,女性的baPWV值快速增加,并显著高于男性(P<0.01)。baPWV与各项指标进行相关性分析发现,年龄与baPWV呈正相关,血糖、血尿酸、收缩压、舒张压均与脉搏波传导速度大小呈高度相关性。结论:动脉粥样硬化早期无创检测技术及其主要指标baP-WV和ABI与心血管危险因素有较好的相关性,在健康体检与心血管病早期风险筛查中具有较好的应用价值。
Objective: To explore the significance of early non-invasive detection of atherosclerosis in healthy physical examination by analyzing the results of 2 995 non-invasive ankle pulse wave velocity (baPWV) and ankle-brachial blood pressure index (ABI) in our hospital. Methods: The physical examination of baPWV and ABI and other physical and biochemical indexes were measured and analyzed according to the age of 5 years at the age of 25-85 years from 2010-07-2011-02. Sex. Results: The average baPWV and anomaly detection rates increased with age in both male and female subjects, and the effect of age on baPWV was greater in women than in men. Between 45 and 54 years old, the baPWV value increased rapidly in women and was significantly higher than that in men (P <0.01). Correlation analysis between baPWV and various indexes showed that age was positively correlated with baPWV, and there was a high correlation between blood glucose, blood uric acid, systolic blood pressure and diastolic blood pressure and pulse wave velocity. Conclusion: The early non-invasive detection of atherosclerosis and its main indicators of baP-WV and ABI have a good correlation with cardiovascular risk factors, and have good value in early screening of physical examination and cardiovascular disease.