患者男,72岁,农民。全身长疙瘩10年,鼻部破溃8年。10年前不明原因于左、右下眼睑下方靠近鼻部出现小米粒大疙瘩,逐渐增大如豌豆大小,中央破溃,无任何不适,曾予手术切除后局部植皮,半年后全身又出现多处类似皮损,不痛不痒,一直未治。8年前,病人左侧鼻翼部原植皮部周围出现黄豆大 Male patient, 72 years old, farmer. The body has been bowed for 10 years and the nose has been broken for 8 years. 10 years ago, unexplained causes of small rice grains near the nose below the left and right lower eyelids, gradually increased, such as the size of peas, the central ulceration, without any discomfort, had local skin graft after surgery, six months later, the body appeared again Similar lesions, superficial, has not been ruled. Eight years ago, a large soybean appeared around the skin of the patient’s left nasal wing.