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LIN28B是一种潜在的致癌基因,其本质为一种高度保守的RNA结合蛋白。LIN28B与女性生殖系统恶性肿瘤,如宫颈癌、卵巢癌、子宫内膜癌的发生、发展密切相关。因而LIN28B有望成为女性生殖系统恶性肿瘤一个新的诊断和治疗靶标。本文现将LIN28B与女性生殖系统恶性肿瘤的相关性做一综述。
LIN28B is a potential oncogene that is essentially a highly conserved RNA-binding protein. LIN28B is closely related to the occurrence and development of female reproductive system malignant tumors such as cervical cancer, ovarian cancer and endometrial cancer. Thus LIN28B is expected to become a new diagnostic and therapeutic target for female reproductive system malignancies. This article will now LIN28B and female reproductive system to make a review of the relevance of malignant tumors.