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0 引言 白蛋白和甘露醇是生产IL-2冻干粉针剂时常用的赋形剂,其目的是保持制剂的生物活性和制剂性状,提高产品的稳定性,并且容易进行冷冻干燥和利于贮藏及运输.我们在实验中利用不同浓度的两种赋形剂生产IL-2冻干制剂,通过检测IL-2的活性,对制剂中白蛋白和甘露醇的保护作用进
0 Introduction Albumin and mannitol are commonly used excipients for the production of IL-2 lyophilized powder for the purpose of maintaining the biological activity of the preparation and the properties of the preparation, improving the stability of the product and facilitating freeze-drying and storage Transport We used two different concentrations of two excipients in our experiments to produce IL-2 lyophilized preparations that were tested for their ability to protect albumin and mannitol by